Chemotherapy Synergizes with Radioimmunotherapy Targeting La Autoantigen in Tumors

Por Al-Ejeh, Fares, Darby, Jocelyn M., Brown, Michael P.
Publicado em 2009

MEK5-ERK5 pathway associates with poor survival of breast cancer patients after systemic treatments

Por Miranda, Mariska, Rozali, Esdy, Khanna, Kum Kum, Al-Ejeh, Fares
Publicado no Oncoscience (2015)

RAD51 inhibition in triple negative breast cancer cells is challenged by compensatory survival signaling and requires rational combination therapy

Por Wiegmans, Adrian P., Miranda, Mariska, Wen, Shu Wen, Al-Ejeh, Fares, Möller, Andreas
Publicado no Oncotarget (2016)

APOMAB®, a La-Specific Monoclonal Antibody, Detects the Apoptotic Tumor Response to Life-Prolonging and DNA-Damaging Chemotherapy

Por Al-Ejeh, Fares, Darby, Jocelyn M., Tsopelas, Chris, Smyth, Douglas, Manavis, Jim, Brown, Michael P.
Publicado em 2009

SCF-FBXO31 E3 Ligase Targets DNA Replication Factor Cdt1 for Proteolysis in the G(2) Phase of Cell Cycle to Prevent Re-replication

Por Johansson, Pegah, Jeffery, Jessie, Al-Ejeh, Fares, Schulz, Renèe B., Callen, David F., Kumar, Raman, Khanna, Kum Kum
Publicado em 2014

EphA2 Is a Therapy Target in EphA2-Positive Leukemias but Is Not Essential for Normal Hematopoiesis or Leukemia

Por Charmsaz, Sara, Beckett, Kirrilee, Smith, Fiona M., Bruedigam, Claudia, Moore, Andrew S., Al-Ejeh, Fares, Lane, Steven W., Boyd, Andrew W.
Publicado no PLoS One (2015)

The La antigen is over-expressed in lung cancer and is a selective dead cancer cell target for radioimmunotherapy using the La-specific antibody APOMAB®

Por Staudacher, Alexander H, Al-Ejeh, Fares, Fraser, Cara K, Darby, Jocelyn M, Roder, David M, Ruszkiewicz, Andrew, Manavis, Jim, Brown, Michael P
Publicado em 2014

Mutant p53 uses p63 as a molecular chaperone to alter gene expression and induce a pro-invasive secretome

Por Neilsen, Paul M., Noll, Jacqueline E., Suetani, Rachel J., Schulz, Renee B., Al-Ejeh, Fares, Evdokiou, Andreas, Lane, David P., Callen, David F.
Publicado em 2011

Rad51 supports triple negative breast cancer metastasis

Por Wiegmans, Adrian P, Al-Ejeh, Fares, Chee, Nicole, Yap, Pei-Yi, Gorski, Julia J, Silva, Leonard Da, Bolderson, Emma, Chenevix-Trench, Georgia, Anderson, Robin, Simpson, Peter T, Lakhani, Sunil R, Khanna, Kum Kum
Publicado em 2014

Kinome profiling reveals breast cancer heterogeneity and identifies targeted therapeutic opportunities for triple negative breast cancer

Por Al-Ejeh, Fares, Miranda, Mariska, Shi, Wei, Simpson, Peter T., Song, Sarah, Vargas, Ana Cristina, Saunus, Jodi M., Smart, Chanel E., Mariasegaram, Mythily, Wiegmans, Adrian P., Chenevix-Trench, Georgia, Lakhani, Sunil R., Khanna, Kum Kum
Publicado em 2014

Essential Developmental, Genomic Stability, and Tumour Suppressor Functions of the Mouse Orthologue of hSSB1/NABP2

Por Shi, Wei, Bain, Amanda L., Schwer, Bjoern, Al-Ejeh, Fares, Smith, Corey, Wong, Lee, Chai, Hua, Miranda, Mariska S., Ho, Uda, Kawaguchi, Makoto, Miura, Yutaka, Finnie, John W., Wall, Meaghan, Heierhorst, Jörg, Wicking, Carol, Spring, Kevin J., Alt, Frederick W., Khanna, Kum Kum
Publicado em 2013

Using the MCF10A/MCF10CA1a Breast Cancer Progression Cell Line Model to Investigate the Effect of Active, Mutant Forms of EGFR in Breast Cancer Development and Treatment Using Gefi...

Por Bessette, Darrell C., Tilch, Erik, Seidens, Tatjana, Quinn, Michael C. J., Wiegmans, Adrian P., Shi, Wei, Cocciardi, Sibylle, McCart-Reed, Amy, Saunus, Jodi M., Simpson, Peter T., Grimmond, Sean M., Lakhani, Sunil R., Khanna, Kum Kum, Waddell, Nic, Al-Ejeh, Fares, Chenevix-Trench, Georgia
Publicado no PLoS One (2015)

Long-range regulators of the lncRNA HOTAIR enhance its prognostic potential in breast cancer

Por Milevskiy, Michael J.G., Al-Ejeh, Fares, Saunus, Jodi M., Northwood, Korinne S., Bailey, Peter J., Betts, Joshua A., McCart Reed, Amy E., Nephew, Kenneth P., Stone, Andrew, Gee, Julia M.W., Dowhan, Dennis H., Dray, Eloise, Shewan, Annette M., French, Juliet D., Edwards, Stacey L., Clark, Susan J., Lakhani, Sunil R., Brown, Melissa A.
Publicado no Hum Mol Genet (2016)