EphA3 Pay-Loaded Antibody Therapeutics for the Treatment of Glioblastoma

The EphA3 receptor has recently emerged as a functional tumour-specific therapeutic target in glioblastoma (GBM). EphA3 is significantly elevated in recurrent disease, is most highly expressed on glioma stem cells (GSCs), and has a functional role in maintaining self-renewal and tumourigenesis. An u...

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書誌詳細
出版年:Cancers (Basel)
主要な著者: Offenhäuser, Carolin, Al-Ejeh, Fares, Puttick, Simon, Ensbey, Kathleen S., Bruce, Zara C., Jamieson, Paul R., Smith, Fiona M., Stringer, Brett W., Carrington, Benjamin, Fuchs, Adrian V., Bell, Craig A., Jeffree, Rosalind, Rose, Stephen, Thurecht, Kristofer J., Boyd, Andrew W., Day, Bryan W.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6316644/
https://ncbi.nlm.nih.gov/pubmed/30562956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers10120519
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