Constrained α-Helical Peptides as Inhibitors of Protein-Protein and Protein-DNA Interactions

Intracellular regulatory pathways are replete with protein-protein and protein-DNA interactions, offering attractive targets for therapeutic interventions. So far, most drugs are targeted toward enzymes and extracellular receptors. Protein-protein and protein-DNA interactions have long been consider...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Roy, Siddhartha, Ghosh, Piya, Ahmed, Israr, Chakraborty, Madhumita, Naiya, Gitashri, Ghosh, Basusree
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315407/
https://ncbi.nlm.nih.gov/pubmed/30567318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines6040118
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