Simultaneous Inhibition of Key Growth Pathways in Melanoma Cells and Tumor Regression by a Designed Bidentate Constrained Helical Peptide

Protein-protein interactions are part of a large number of signaling networks and potential targets for drug development. However, discovering molecules that can specifically inhibit such interactions is a major challenge. S100B, a calcium-regulated protein, plays a crucial role in the proliferation...

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Huvudupphovsmän: Dhar, Amlanjyoti, Mallick, Shampa, Ghosh, Piya, Maiti, Atanu, Ahmed, Israr, Bhattacharyya, Seemana, Mandal, Tapashi, Manna, Asit, Roy, Koushik, Singh, Sandeep, Nayak, Dipak Kumar, Wilder, Paul T., Markowitz, Joseph, Weber, David J., Ghosh, Mrinal K., Chattopadhyay, Samit, Guha, Rajdeep, Konar, Aditya, Bandyopadhyay, Santu, Roy, Siddhartha
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4107132/
https://ncbi.nlm.nih.gov/pubmed/24839139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bip.22505
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