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Constrained α-Helical Peptides as Inhibitors of Protein-Protein and Protein-DNA Interactions

Intracellular regulatory pathways are replete with protein-protein and protein-DNA interactions, offering attractive targets for therapeutic interventions. So far, most drugs are targeted toward enzymes and extracellular receptors. Protein-protein and protein-DNA interactions have long been consider...

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Detalhes bibliográficos
Main Authors: Siddhartha Roy, Piya Ghosh, Israr Ahmed, Madhumita Chakraborty, Gitashri Naiya, Basusree Ghosh
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2018-12-01
Colecção:Biomedicines
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Acesso em linha:https://www.mdpi.com/2227-9059/6/4/118
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