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TNF-α: An Activator of CD4+FoxP3+TNFR2+Regulatory T Cells

TNF-α (TNF) is a pleiotropic cytokine which can have proinflammatory or immunosuppressive effects, depending on the context, duration of exposure and disease state. The basis for the opposing actions of TNF remains elusive. The growing appreciation of CD4+FoxP3+ regulatory T cells (Tregs), which com...

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Bibliographic Details
Published in:Curr Dir Autoimmun
Main Authors: Chen, Xin, Oppenheim, Joost J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314650/
https://ncbi.nlm.nih.gov/pubmed/20173391
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000289201
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