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Inotropic interventions do not change the resting state of myosin motors during cardiac diastole

When striated (skeletal and cardiac) muscle is in its relaxed state, myosin motors are packed in helical tracks on the surface of the thick filament, folded toward the center of the sarcomere, and unable to bind actin or hydrolyze ATP (OFF state). This raises the question of whatthe mechanism is tha...

詳細記述

保存先:
書誌詳細
出版年:J Gen Physiol
主要な著者: Caremani, Marco, Pinzauti, Francesca, Powers, Joseph D., Governali, Serena, Narayanan, Theyencheri, Stienen, Ger J.M., Reconditi, Massimo, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314382/
https://ncbi.nlm.nih.gov/pubmed/30510036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812196
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