Inotropic interventions do not change the resting state of myosin motors during cardiac diastole

When striated (skeletal and cardiac) muscle is in its relaxed state, myosin motors are packed in helical tracks on the surface of the thick filament, folded toward the center of the sarcomere, and unable to bind actin or hydrolyze ATP (OFF state). This raises the question of whatthe mechanism is tha...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Gen Physiol
Main Authors: Caremani, Marco, Pinzauti, Francesca, Powers, Joseph D., Governali, Serena, Narayanan, Theyencheri, Stienen, Ger J.M., Reconditi, Massimo, Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314382/
https://ncbi.nlm.nih.gov/pubmed/30510036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812196
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados