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Myosin filament activation in the heart is tuned to the mechanical task

The mammalian heart pumps blood through the vessels, maintaining the dynamic equilibrium in a circulatory system driven by two pumps in series. This vital function is based on the fine-tuning of cardiac performance by the Frank–Starling mechanism that relates the pressure exerted by the contracting...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Reconditi, Massimo, Caremani, Marco, Pinzauti, Francesca, Powers, Joseph D., Narayanan, Theyencheri, Stienen, Ger J. M., Linari, Marco, Lombardi, Vincenzo, Piazzesi, Gabriella
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373356/
https://ncbi.nlm.nih.gov/pubmed/28265101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1619484114
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