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Cholesterol intake and statin use regulate neuronal G protein-gated inwardly rectifying potassium channels

Cholesterol, a critical component of the cellular plasma membrane, is essential for normal neuronal function. Cholesterol content is highest in the brain, where most cholesterol is synthesized de novo; HMG-CoA reductase controls the synthesis rate. Despite strict control, elevated blood cholesterol...

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Dades bibliogràfiques
Publicat a:J Lipid Res
Autors principals: Bukiya, Anna N., Blank, Paul S., Rosenhouse-Dantsker, Avia
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Biochemistry and Molecular Biology 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314255/
https://ncbi.nlm.nih.gov/pubmed/30420402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M081240
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