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Regulation of Kv11.1 potassium channel C-terminal isoform expression by the RNA-binding proteins HuR and HuD

The potassium voltage-gated channel subfamily H member 2 (KCNH2) gene encodes the Kv11.1 potassium channel, which conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative polyadenylation and forms a functional, full-length Kv11.1a isoform if exon 1...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314146/
https://ncbi.nlm.nih.gov/pubmed/30377250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003720
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