FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

Erythropoietin (EPO) signaling is critical to many processes essential to terminal erythropoiesis. Despite the centrality of iron metabolism to erythropoiesis, the mechanisms by which EPO regulates iron status are not well-understood. To this end, here we profiled gene expression in EPO-treated 32D...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Yien, Yvette Y., Shi, Jiahai, Chen, Caiyong, Cheung, Jesmine T. M., Grillo, Anthony S., Shrestha, Rishna, Li, Liangtao, Zhang, Xuedi, Kafina, Martin D., Kingsley, Paul D., King, Matthew J., Ablain, Julien, Li, Hojun, Zon, Leonard I., Palis, James, Burke, Martin D., Bauer, Daniel E., Orkin, Stuart H., Koehler, Carla M., Phillips, John D., Kaplan, Jerry, Ward, Diane M., Lodish, Harvey F., Paw, Barry H.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2018
Fag:
Metabolism
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314115/
https://ncbi.nlm.nih.gov/pubmed/30366982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002742
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