MicroRNA‐210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes

BACKGROUND: MicroRNA‐210 (miR‐210) increases in hypoxia and regulates mitochondrial respiration through modulation of iron‐sulfur cluster assembly proteins (ISCU1/2), a protein that is involved in Fe/S cluster synthesis. However, it is not known how miR‐210 affects cellular iron levels or production...

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Hlavní autoři: Qiao, Aijun, Khechaduri, Arineh, Kannan Mutharasan, R., Wu, Rongxue, Nagpal, Varun, Ardehali, Hossein
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2013
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3647255/
https://ncbi.nlm.nih.gov/pubmed/23608607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000121
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