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MicroRNA‐210 Decreases heme Levels by Targeting Ferrochelatase in Cardiomyocytes
BACKGROUND: MicroRNA‐210 (miR‐210) increases in hypoxia and regulates mitochondrial respiration through modulation of iron‐sulfur cluster assembly proteins (ISCU1/2), a protein that is involved in Fe/S cluster synthesis. However, it is not known how miR‐210 affects cellular iron levels or production...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Blackwell Publishing Ltd
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3647255/ https://ncbi.nlm.nih.gov/pubmed/23608607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.113.000121 |
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