FAM210B is an erythropoietin target and regulates erythroid heme synthesis by controlling mitochondrial iron import and ferrochelatase activity

Erythropoietin (EPO) signaling is critical to many processes essential to terminal erythropoiesis. Despite the centrality of iron metabolism to erythropoiesis, the mechanisms by which EPO regulates iron status are not well-understood. To this end, here we profiled gene expression in EPO-treated 32D...

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Vydáno v:J Biol Chem
Hlavní autoři: Yien, Yvette Y., Shi, Jiahai, Chen, Caiyong, Cheung, Jesmine T. M., Grillo, Anthony S., Shrestha, Rishna, Li, Liangtao, Zhang, Xuedi, Kafina, Martin D., Kingsley, Paul D., King, Matthew J., Ablain, Julien, Li, Hojun, Zon, Leonard I., Palis, James, Burke, Martin D., Bauer, Daniel E., Orkin, Stuart H., Koehler, Carla M., Phillips, John D., Kaplan, Jerry, Ward, Diane M., Lodish, Harvey F., Paw, Barry H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2018
Témata:
Metabolism
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314115/
https://ncbi.nlm.nih.gov/pubmed/30366982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002742
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