Virus-Like Particles Are a Superior Platform for Presenting M2e Epitopes to Prime Humoral and Cellular Immunity against Influenza Virus

Influenza virus M2 protein has a highly conserved ectodomain (M2e) as a cross-protective antigenic target. We investigated the antigenic and immunogenic properties of tandem repeat M2e (5xM2e) proteins and virus-like particles (5xM2e VLP) to better understand how VLP and protein platform vaccines in...

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Détails bibliographiques
Publié dans:Vaccines (Basel)
Auteurs principaux: Kim, Ki-Hye, Kwon, Young-Man, Lee, Young-Tae, Kim, Min-Chul, Hwang, Hye Suk, Ko, Eun-Ju, Lee, Youri, Choi, Hyo-Jick, Kang, Sang-Moo
Format: Artigo
Langue:Inglês
Publié: MDPI 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6313937/
https://ncbi.nlm.nih.gov/pubmed/30241300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/vaccines6040066
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