Virus-like particles presenting flagellin exhibit unique adjuvant effects on eliciting T helper type 1 humoral and cellular immune responses to poor immunogenic influenza virus M2e protein vaccine

Current licensed adjuvants including aluminum hydroxide (alum) bias immune responses toward T helper type 2 (Th2) immune responses. We tested whether virus-like particles presenting flagellin (Flag VLP) exhibit adjuvant effects on eliciting Th1 type immune responses and improving the efficacy of poo...

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Publicado no:Virology
Main Authors: Kim, Ki-Hye, Kwon, Young-Man, Lee, Young-Tae, Hwang, Hye Suk, Kim, Min-Chul, Ko, Eun-Ju, Wang, Bao-Zhong, Quan, Fu-Shi, Kang, Sang-Moo
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190693/
https://ncbi.nlm.nih.gov/pubmed/30199754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2018.08.019
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