Virus-Like Particle Vaccine Containing the F Protein of Respiratory Syncytial Virus Confers Protection without Pulmonary Disease by Modulating Specific Subsets of Dendritic Cells and Effector T Cells

There is no licensed vaccine against respiratory syncytial virus (RSV) since the failure of formalin-inactivated RSV (FI-RSV) due to its vaccine-enhanced disease. We investigated immune correlates conferring protection without causing disease after intranasal immunization with virus-like particle va...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kim, Ki-Hye, Lee, Young-Tae, Hwang, Hye Suk, Kwon, Young-Man, Kim, Min-Chul, Ko, Eun-Ju, Lee, Jong Seok, Lee, Youri, Kang, Sang-Moo
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2015
Sujets:
Vaccines and Antiviral Agents
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4645681/
https://ncbi.nlm.nih.gov/pubmed/26355098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02018-15
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