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A Self-Deleting AAV-CRISPR System for In Vivo Genome Editing
Adeno-associated viral (AAV) vectors packaging the CRISPR-Cas9 system (AAV-CRISPR) can efficiently modify disease-relevant genes in somatic tissues with high efficiency. AAV vectors are a preferred delivery vehicle for tissue-directed gene therapy because of their ability to achieve sustained expres...
שמור ב:
| הוצא לאור ב: | Mol Ther Methods Clin Dev |
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| Main Authors: | , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society of Gene & Cell Therapy
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6313841/ https://ncbi.nlm.nih.gov/pubmed/30619914 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.11.009 |
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