VP4- and VP7-specific antibodies mediate heterotypic immunity to rotavirus in humans

Human rotaviruses (RVs) are the leading cause of severe diarrhea in young children worldwide. The molecular mechanisms underlying the rapid induction of heterotypic protective immunity to RV, which provides the basis for the efficacy of licensed monovalent RV vaccines, have remained unknown for more...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Nair, Nitya, Feng, Ningguo, Blum, Lisa K., Sanyal, Mrinmoy, Ding, Siyuan, Jiang, Baoming, Sen, Adrish, Morton, John M., He, Xiao-Song, Robinson, William H., Greenberg, Harry B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312383/
https://ncbi.nlm.nih.gov/pubmed/28637924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aam5434
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