Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells

We previously generated 32 rotavirus-specific (RV-specific) recombinant monoclonal antibodies (mAbs) derived from B cells isolated from human intestinal resections. Twenty-four of these mAbs were specific for the VP8* fragment of RV VP4, and most (20 of 24) were non-neutralizing when tested in the c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Feng, Ningguo, Hu, Liya, Ding, Siyuan, Sanyal, Mrinmoy, Zhao, Boyang, Sankaran, Banumathi, Ramani, Sasirekha, McNeal, Monica, Yasukawa, Linda L., Song, Yanhua, Prasad, B.V. Venkataram, Greenberg, Harry B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2019
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6715378/
https://ncbi.nlm.nih.gov/pubmed/31403468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI128382
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