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Accurate Estimation of Ligand Binding Affinity Changes upon Protein Mutation
[Image: see text] The design of proteins with novel ligand-binding functions holds great potential for application in biomedicine and biotechnology. However, our ability to engineer ligand-binding proteins is still limited, and current approaches rely primarily on experimentation. Computation could...
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| Pubblicato in: | ACS Cent Sci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Chemical Society
2018
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311686/ https://ncbi.nlm.nih.gov/pubmed/30648154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.8b00717 |
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