Wordt geladen...

Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein-Protein Binding Affinity Upon Mutation

Computationally modeling changes in binding free energies upon mutation (interface ΔΔG) allows large-scale prediction and perturbation of protein-protein interactions. Additionally, methods that consider and sample relevant conformational plasticity should be able to achieve higher prediction accura...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:J Phys Chem B
Hoofdauteurs: Barlow, Kyle A., Conchúir, Shane O, Thompson, Samuel, Suresh, Pooja, Lucas, James E., Heinonen, Markus, Kortemme, Tanja
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980710/
https://ncbi.nlm.nih.gov/pubmed/29401388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.7b11367
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!