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The mitochondrial inner membrane protein MPV17 prevents uracil accumulation in mitochondrial DNA
Mitochondrial inner membrane protein MPV17 is a protein of unknown function that is associated with mitochondrial DNA (mtDNA)-depletion syndrome (MDS). MPV17 loss-of-function has been reported to result in tissue-specific nucleotide pool imbalances, which can occur in states of perturbed folate-medi...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6311524/ https://ncbi.nlm.nih.gov/pubmed/30385507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004788 |
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