Загрузка...
Autoimmunity to hypocretin and molecular mimicry to flu in type 1 narcolepsy
Type 1 narcolepsy (T1N) is caused by hypocretin/orexin (HCRT) neuronal loss. Association with the HLA DQB1*06:02/DQA1*01:02 (98% vs. 25%) heterodimer (DQ0602), T cell receptors (TCR) and other immune loci suggest autoimmunity but autoantigens are unknown. Onset is seasonal and associated with influe...
Сохранить в:
| Опубликовано в: : | Proc Natl Acad Sci U S A |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2018
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310865/ https://ncbi.nlm.nih.gov/pubmed/30541895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818150116 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|