Profiling proliferative cells and their progeny in damaged murine hearts

The significance of cardiac stem cell (CSC) populations for cardiac regeneration remains disputed. Here, we apply the most direct definition of stem cell function (the ability to replace lost tissue through cell division) to interrogate the existence of CSCs. By single-cell mRNA sequencing and genet...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Kretzschmar, Kai, Post, Yorick, Bannier-Hélaouët, Marie, Mattiotti, Andrea, Drost, Jarno, Basak, Onur, Li, Vivian S. W., van den Born, Maaike, Gunst, Quinn D., Versteeg, Danielle, Kooijman, Lieneke, van der Elst, Stefan, van Es, Johan H., van Rooij, Eva, van den Hoff, Maurice J. B., Clevers, Hans
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6310797/
https://ncbi.nlm.nih.gov/pubmed/30530645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1805829115
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