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Enteroendocrine cells switch hormone expression along the crypt-to-villus BMP signaling gradient
Enteroendocrine cells (EECs) control a wide range of physiological processes linked to metabolism1. We show that EECs hormones are differentially expressed between crypts (e.g. Glp1) and villi (e.g. Secretin). As demonstrated by single cell mRNA sequencing, BMP4 signals can reprogram the expressed r...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276989/ https://ncbi.nlm.nih.gov/pubmed/30038251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41556-018-0143-y |
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