טוען...
Novel Treatment of Hypertension by Specifically Targeting E2F for Restoration of Endothelial Dihydrofolate Reductase and eNOS Function Under Oxidative Stress
We have shown that hydrogen peroxide (H(2)O(2)) downregulates tetrahydrobiopterin (H(4)B) salvage enzyme dihydrofolate reductase (DHFR) to result in eNOS uncoupling and elevated blood pressure. Here we aimed to delineate molecular mechanisms underlying H(2)O(2) downregulation of endothelial DHFR by...
שמור ב:
| הוצא לאור ב: | Hypertension |
|---|---|
| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2019
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6310047/ https://ncbi.nlm.nih.gov/pubmed/30571557 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.118.11643 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|