COX-2 Inhibition Potentiates Anti-Angiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

Anti-angiogenic agents that block Vascular Endothelial Growth Factor (VEGF) signaling are important components of current cancer treatment modalities but are limited by alternative ill-defined angiogenesis mechanisms that allow persistent tumor vascularization in the face of continued VEGF pathway b...

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Опубликовано в: :Sci Transl Med
Главные авторы: Xu, Lihong, Stevens, Janine, Hilton, Mary Beth, Seaman, Steven, Conrads, Thomas P., Veenstra, Timothy D., Logsdon, Daniel, Morris, Holly, Swing, Deborah A., Patel, Nimit L., Kalen, Joseph, Haines, Diana C., Zudaire, Enrique, Croix, Brad St.
Формат: Artigo
Язык:Inglês
Опубликовано: 2014
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309995/
https://ncbi.nlm.nih.gov/pubmed/24964992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008455
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