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Improving VEGF-targeted therapies through inhibition of COX-2/PGE(2) signaling

Antiangiogenic agents targeting the vascular endothelial growth factor A (VEGFA) pathway play an important role in current cancer treatment modalities but are limited by alternative angiogenesis mechanisms. Recent studies suggest that enhanced signaling through a COX-2/PGE(2) axis contributes to VEG...

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Détails bibliographiques
Publié dans:Mol Cell Oncol
Auteurs principaux: Xu, Lihong, Croix, Brad St.
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4905212/
https://ncbi.nlm.nih.gov/pubmed/27308371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/23723548.2014.969154
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