A carregar...
Key role of the positive feedback between PGE(2) and COX2 in the biology of myeloid-derived suppressor cells
PGE(2) is the key factor needed for MDSCs development, accumulation and functional stability. PGE(2) initiates an EP2/EP4-mediated positive feedback between COX2 and PGE(2) in monocytic precursors, redirecting dendritic cell differentiation to MDSCs. COX2- or EP2/EP4- blockade abrogates MDSC functio...
Na minha lista:
| Main Authors: | , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429587/ https://ncbi.nlm.nih.gov/pubmed/22934275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.19681 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|