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Host-Derived Tumor Endothelial Marker 8 (TEM8) Promotes the Growth of Melanoma

TEM8 was initially identified as a gene overexpressed in the vasculature of human tumors and was subsequently identified as an anthrax toxin receptor. To assess the functional role of TEM8, we disrupted the TEM8 gene in mice by targeted homologous recombination. TEM8(−/−) mice were viable and reache...

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Bibliografische gegevens
Hoofdauteurs: Cullen, Mike, Seaman, Steven, Chaudhary, Amit, Yang, Mi Young, Hilton, Mary Beth, Logsdon, Daniel, Haines, Diana C., Tessarollo, Lino, St. Croix, Brad
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721800/
https://ncbi.nlm.nih.gov/pubmed/19622764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1086
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