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Host-Derived Tumor Endothelial Marker 8 (TEM8) Promotes the Growth of Melanoma

TEM8 was initially identified as a gene overexpressed in the vasculature of human tumors and was subsequently identified as an anthrax toxin receptor. To assess the functional role of TEM8, we disrupted the TEM8 gene in mice by targeted homologous recombination. TEM8(−/−) mice were viable and reache...

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Detalhes bibliográficos
Main Authors: Cullen, Mike, Seaman, Steven, Chaudhary, Amit, Yang, Mi Young, Hilton, Mary Beth, Logsdon, Daniel, Haines, Diana C., Tessarollo, Lino, St. Croix, Brad
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721800/
https://ncbi.nlm.nih.gov/pubmed/19622764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1086
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