GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier

Every organ in the body requires blood vessels for efficient delivery of oxygen and nutrients, but independent vascular beds are highly specialized to meet the individual needs of specific organs. The vasculature of the brain is tightly sealed, with blood–brain barrier (BBB) properties developing co...

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Detalhes bibliográficos
Main Authors: Cullen, Mike, Elzarrad, Mohammed K., Seaman, Steven, Zudaire, Enrique, Stevens, Janine, Yang, Mi Young, Li, Xiujie, Chaudhary, Amit, Xu, Lihong, Hilton, Mary Beth, Logsdon, Daniel, Hsiao, Emily, Stein, Erica V., Cuttitta, Frank, Haines, Diana C., Nagashima, Kunio, Tessarollo, Lino, St. Croix, Brad
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078373/
https://ncbi.nlm.nih.gov/pubmed/21421844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017192108
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