GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood–brain barrier

Every organ in the body requires blood vessels for efficient delivery of oxygen and nutrients, but independent vascular beds are highly specialized to meet the individual needs of specific organs. The vasculature of the brain is tightly sealed, with blood–brain barrier (BBB) properties developing co...

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Главные авторы: Cullen, Mike, Elzarrad, Mohammed K., Seaman, Steven, Zudaire, Enrique, Stevens, Janine, Yang, Mi Young, Li, Xiujie, Chaudhary, Amit, Xu, Lihong, Hilton, Mary Beth, Logsdon, Daniel, Hsiao, Emily, Stein, Erica V., Cuttitta, Frank, Haines, Diana C., Nagashima, Kunio, Tessarollo, Lino, St. Croix, Brad
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2011
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3078373/
https://ncbi.nlm.nih.gov/pubmed/21421844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1017192108
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