Essential Regulation of Lung Surfactant Homeostasis by the Orphan G-protein Coupled Receptor GPR116

GPR116 is an orphan seven-pass transmembrane receptor of previously unknown function. Global disruption of the Gpr116 gene in mice revealed an unexpected, critical role for this receptor in lung surfactant homeostasis, resulting in progressive accumulation of surfactant lipids and proteins in the al...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Yang, Mi Young, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Nagashima, Kunio, Burks, Christina M., Tessarollo, Lino, Ivanova, Pavlina T., Brown, H. Alex, Umstead, Todd M., Floros, Joanna, Chroneos, Zissis C., St. Croix, Brad
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2013
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3695742/
https://ncbi.nlm.nih.gov/pubmed/23684610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.04.019
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