COX-2 Inhibition Potentiates Anti-Angiogenic Cancer Therapy and Prevents Metastasis in Preclinical Models

Anti-angiogenic agents that block Vascular Endothelial Growth Factor (VEGF) signaling are important components of current cancer treatment modalities but are limited by alternative ill-defined angiogenesis mechanisms that allow persistent tumor vascularization in the face of continued VEGF pathway b...

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Detalhes bibliográficos
Publicado no:Sci Transl Med
Main Authors: Xu, Lihong, Stevens, Janine, Hilton, Mary Beth, Seaman, Steven, Conrads, Thomas P., Veenstra, Timothy D., Logsdon, Daniel, Morris, Holly, Swing, Deborah A., Patel, Nimit L., Kalen, Joseph, Haines, Diana C., Zudaire, Enrique, Croix, Brad St.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309995/
https://ncbi.nlm.nih.gov/pubmed/24964992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.3008455
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