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Representing the Process of Inflammation as Key Events in Adverse Outcome Pathways

Inflammation is an important biological process involved in many target organ toxicities. However, there has been little consensus on how to represent inflammatory processes using the adverse outcome pathway (AOP) framework. In particular, there were concerns that inflammation was not being represen...

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Veröffentlicht in:Toxicol Sci
Hauptverfasser: Villeneuve, Daniel L., Landesmann, Brigitte, Allavena, Paola, Ashley, Noah, Bal-Price, Anna, Corsini, Emanuela, Halappanavar, Sabina, Hussell, Tracy, Laskin, Debra, Lawrence, Toby, Nikolic-Paterson, David, Pallardy, Marc, Paini, Alicia, Pieters, Raymond, Roth, Robert, Tschudi-Monnet, Florianne
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309953/
https://ncbi.nlm.nih.gov/pubmed/29850905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfy047
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