Translatability and transferability of in silico models: Context of use switching to predict the effects of environmental chemicals on the immune system

Immunotoxicity hazard identification of chemicals aims to evaluate the potential for unintended effects of chemical exposure on the immune system. Perfluorinated alkylate substances (PFAS), such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA), are persistent, globally dissemina...

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Detalhes bibliográficos
Main Authors: Francesco Pappalardo, Giulia Russo, Emanuela Corsini, Alicia Paini, Andrew Worth
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2022-01-01
Colecção:Computational and Structural Biotechnology Journal
Assuntos:
In silico trials
Immune system
PFAS
Risk-assessment
Vaccines
Immunotoxicity
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S200103702200099X
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