Effects of the PPAR-β agonist GW501516 in an in vitro model of brain inflammation and antibody-induced demyelination

BACKGROUND: Brain inflammation plays a central role in numerous brain pathologies, including multiple sclerosis (MS). Microglial cells and astrocytes are the effector cells of neuroinflammation. They can be activated also by agents such as interferon-γ (IFN-γ) and lipopolysaccharide (LPS). Peroxisom...

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Detalhes bibliográficos
Main Authors: Defaux, Antoinette, Zurich, Marie-Gabrielle, Braissant, Olivier, Honegger, Paul, Monnet-Tschudi, Florianne
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2687435/
https://ncbi.nlm.nih.gov/pubmed/19422681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-6-15
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