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Insights into the Molecular Mechanism of Triptan Transport by P-glycoprotein

The P-glycoprotein (Pgp) transporter reduces the penetration of a chemically diverse range of neurotherapeutics at the blood-brain barrier (BBB), but the molecular features of drugs and drug-Pgp interactions that drive transport remain to be clarified. In particular, the triptan neurotherapeutics, e...

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Bibliografske podrobnosti
izdano v:J Pharm Sci
Main Authors: Wilt, Laura A., Nguyen, Diana, Roberts, Arthur G.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309430/
https://ncbi.nlm.nih.gov/pubmed/28283434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.02.032
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