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Insights into the Molecular Mechanism of Triptan Transport by P-glycoprotein
The P-glycoprotein (Pgp) transporter reduces the penetration of a chemically diverse range of neurotherapeutics at the blood-brain barrier (BBB), but the molecular features of drugs and drug-Pgp interactions that drive transport remain to be clarified. In particular, the triptan neurotherapeutics, e...
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| Published in: | J Pharm Sci |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309430/ https://ncbi.nlm.nih.gov/pubmed/28283434 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.xphs.2017.02.032 |
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