P-Glycoprotein-ATPase Modulation: The Molecular Mechanisms

P-glycoprotein-ATPase is an efflux transporter of broad specificity that counteracts passive allocrit influx. Understanding the rate of allocrit transport therefore matters. Generally, the rates of allocrit transport and ATP hydrolysis decrease exponentially with increasing allocrit affinity to the...

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Bibliographic Details
Main Authors: Li-Blatter, Xiaochun, Beck, Andreas, Seelig, Anna
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Channels and Transporters
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309411/
https://ncbi.nlm.nih.gov/pubmed/22455921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.02.018
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