PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

TGFβ signaling controls diverse normal developmental processes and pathogenesis of diseases including cancer and autoimmune and fibrotic diseases. TGFβ responses are generally mediated through transcriptional functions of Smads. A key step in TGFβ signaling is ligand-induced phosphorylation of recep...

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Publicat a:Cell
Autors principals: Lin, Xia, Duan, Xueyan, Liang, Yao-Yun, Su, Ying, Wrighton, Katharine H., Long, Jianyin, Hu, Min, Davis, Candi M., Wang, Jinrong, Brunicardi, F. Charles, Shi, Yigong, Chen, Ye-Guang, Meng, Anming, Feng, Xin-Hua
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309366/
https://ncbi.nlm.nih.gov/pubmed/16751101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.03.044
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