PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

TGFβ signaling controls diverse normal developmental processes and pathogenesis of diseases including cancer and autoimmune and fibrotic diseases. TGFβ responses are generally mediated through transcriptional functions of Smads. A key step in TGFβ signaling is ligand-induced phosphorylation of recep...

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Bibliographic Details
Published in:	Cell
Main Authors:	Lin, Xia, Duan, Xueyan, Liang, Yao-Yun, Su, Ying, Wrighton, Katharine H., Long, Jianyin, Hu, Min, Davis, Candi M., Wang, Jinrong, Brunicardi, F. Charles, Shi, Yigong, Chen, Ye-Guang, Meng, Anming, Feng, Xin-Hua
Format:	Artigo
Language:	Inglês
Published:	2006
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6309366/ https://ncbi.nlm.nih.gov/pubmed/16751101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.03.044
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PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

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