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Nuclear export of Smad2 and Smad3 by RanBP3 facilitates termination of TGF-β signaling
Smad2 and Smad3 (Smad2/3) are key intracellular signal transducers for TGF-β signaling and their transcriptional activities are controlled through reversible phosphorylation and nucleocytoplasmic shuttling. However, the precise mechanism underlying nuclear export of Smad2/3 remains elusive. Here we...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676691/ https://ncbi.nlm.nih.gov/pubmed/19289081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.01.022 |
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