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PPM1A dephosphorylates RanBP3 to enable efficient nuclear export of Smad2 and Smad3
Smad2 and Smad3 (Smad2/3) are essential signal transducers and transcription factors in the canonical transforming growth factor-β (TGF-β) signalling pathway. Active Smad2/3 signalling in the nucleus is terminated by dephosphorylation and subsequent nuclear export of Smad2/3. Here we report that pro...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3207100/ https://ncbi.nlm.nih.gov/pubmed/21960005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2011.174 |
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