RanBP3 influences interactions between CRM1 and its nuclear protein export substrates

We investigated the role of RanBP3, a nuclear member of the Ran-binding protein 1 family, in CRM1-mediated protein export in higher eukaryotes. RanBP3 interacts directly with CRM1 and also forms a trimeric complex with CRM1 and RanGTP. However, RanBP3 does not bind to CRM1 like an export substrate....

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Autores principales: Englmeier, Ludwig, Fornerod, Maarten, Bischoff, F. Ralf, Petosa, Carlo, Mattaj, Iain W., Kutay, Ulrike
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2001
Materias:
Scientific Reports
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1084078/
https://ncbi.nlm.nih.gov/pubmed/11571268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kve200
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