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PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling
TGFβ signaling controls diverse normal developmental processes and pathogenesis of diseases including cancer and autoimmune and fibrotic diseases. TGFβ responses are generally mediated through transcriptional functions of Smads. A key step in TGFβ signaling is ligand-induced phosphorylation of recep...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2006
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309366/ https://ncbi.nlm.nih.gov/pubmed/16751101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.03.044 |
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