PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

TGFβ signaling controls diverse normal developmental processes and pathogenesis of diseases including cancer and autoimmune and fibrotic diseases. TGFβ responses are generally mediated through transcriptional functions of Smads. A key step in TGFβ signaling is ligand-induced phosphorylation of recep...

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Gepubliceerd in:Cell
Hoofdauteurs: Lin, Xia, Duan, Xueyan, Liang, Yao-Yun, Su, Ying, Wrighton, Katharine H., Long, Jianyin, Hu, Min, Davis, Candi M., Wang, Jinrong, Brunicardi, F. Charles, Shi, Yigong, Chen, Ye-Guang, Meng, Anming, Feng, Xin-Hua
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2006
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309366/
https://ncbi.nlm.nih.gov/pubmed/16751101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.03.044
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