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PPM1A Functions as a Smad Phosphatase to Terminate TGFβ Signaling

TGFβ signaling controls diverse normal developmental processes and pathogenesis of diseases including cancer and autoimmune and fibrotic diseases. TGFβ responses are generally mediated through transcriptional functions of Smads. A key step in TGFβ signaling is ligand-induced phosphorylation of recep...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Lin, Xia, Duan, Xueyan, Liang, Yao-Yun, Su, Ying, Wrighton, Katharine H., Long, Jianyin, Hu, Min, Davis, Candi M., Wang, Jinrong, Brunicardi, F. Charles, Shi, Yigong, Chen, Ye-Guang, Meng, Anming, Feng, Xin-Hua
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6309366/
https://ncbi.nlm.nih.gov/pubmed/16751101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2006.03.044
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