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PKCθ via Activating Transcription Factor 2-mediated CD36 Expression and Foam Cell Formation of Ly6C(hi) Cells Contributes to Atherosclerosis
BACKGROUND: Although the role of thrombin in atherothrombosis is well studied, its role in the pathogenesis of diet-induced atherosclerosis is not known. METHODS: Using a mouse model of diet-induced atherosclerosis and molecular biological approaches, here we have explored the role of thrombin and i...
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| Udgivet i: | Circulation |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6309268/ https://ncbi.nlm.nih.gov/pubmed/29991487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.118.034083 |
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