Novel ligand-based docking; molecular dynamic simulations; and absorption, distribution, metabolism, and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimer's disease

Acetylcholinesterase (AChE) plays an important role in Alzheimer's disease (AD). The excessive activity of AChE causes various neuronal problems, particularly dementia and neuronal cell deaths. Generally, anti-AChE drugs induce some serious neuronal side effects in humans. Therefore, this study...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Pharm Anal
Autores principales: Vijayakumar, Subramaniyan, Manogar, Palani, Prabhu, Srinivasan, Sanjeevkumar Singh, Ram Avadhar
Formato: Artigo
Lenguaje:Inglês
Publicado: Xi'an Jiaotong University 2018
Materias:
Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308024/
https://ncbi.nlm.nih.gov/pubmed/30595949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.07.006
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares