Novel ligand-based docking; molecular dynamic simulations; and absorption, distribution, metabolism, and excretion approach to analyzing potential acetylcholinesterase inhibitors for Alzheimer's disease

Acetylcholinesterase (AChE) plays an important role in Alzheimer's disease (AD). The excessive activity of AChE causes various neuronal problems, particularly dementia and neuronal cell deaths. Generally, anti-AChE drugs induce some serious neuronal side effects in humans. Therefore, this study...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Pharm Anal
Päätekijät: Vijayakumar, Subramaniyan, Manogar, Palani, Prabhu, Srinivasan, Sanjeevkumar Singh, Ram Avadhar
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Xi'an Jiaotong University 2018
Aiheet:
Original Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6308024/
https://ncbi.nlm.nih.gov/pubmed/30595949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2017.07.006
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