l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans

BACKGROUND.l-Carnitine, an abundant nutrient in red meat, accelerates atherosclerosis in mice via gut microbiota–dependent formation of trimethylamine (TMA) and trimethylamine N-oxide (TMAO) via a multistep pathway involving an atherogenic intermediate, γ-butyrobetaine (γBB). The contribution of γBB...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Koeth, Robert A., Lam-Galvez, Betzabe Rachel, Kirsop, Jennifer, Wang, Zeneng, Levison, Bruce S., Gu, Xiaodong, Copeland, Matthew F., Bartlett, David, Cody, David B., Dai, Hong J., Culley, Miranda K., Li, Xinmin S., Fu, Xiaoming, Wu, Yuping, Li, Lin, DiDonato, Joseph A., Tang, W.H. Wilson, Garcia-Garcia, Jose Carlos, Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Clinical Medicine
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6307959/
https://ncbi.nlm.nih.gov/pubmed/30530985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI94601
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares