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Intestinal Microbial Metabolism of Phosphatidylcholine and Cardiovascular Risk

BACKGROUND: Recent studies in animals have shown a mechanistic link between intestinal microbial metabolism of the choline moiety in dietary phosphatidylcholine (lecithin) and coronary artery disease through the production of a proatherosclerotic metabolite, trimethylamine-N-oxide (TMAO). We investi...

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Detalhes bibliográficos
Main Authors: Tang, W.H. Wilson, Wang, Zeneng, Levison, Bruce S., Koeth, Robert A., Britt, Earl B., Fu, Xiaoming, Wu, Yuping, Hazen, Stanley L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3701945/
https://ncbi.nlm.nih.gov/pubmed/23614584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1109400
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